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Essay on A SUMMARY OF GENE THERAPY | ||
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This is the first 1,000 characters of 647 words (2.59 pages) in the essay titled A SUMMARY OF GENE THERAPY Many diseases seen today are the result of a defective gene in the DNA of the patient and can not be cured using the traditional methods such as antibiotics and antiviral medication. The victims are now looking to gene therapy as a potential cure for their problems. Bob Williamson introduces us the concept, procedures, and problems associated with gene therapy in his article, “Gene Therapy”.Along with the appearance of the recombinant DNA technology, it becomes possible for human beings to isolate, study, and change gene in the laboratory. Gene Therapy is the process of replacing a defective gene inside a patient’s DNA with a working gene that will produce the correct gene products. The genetic diseases “in which a single known gene does not function properly”, such as sickle cell anaemia, thalassaemia and Lesch-Nyhan syndrome, are most suitable to be treated with the gene therapy. There are two types of gene therapy in curing these diseases, patient therapy and embryo therapy. In the process of the patient therapy, the first step is identifying the defective gene and isolating a normal counterpart. “ To obtain correct gene action, it may be necessary to put it into the correct site on the host cell chromosome, or even to delete the defective gene”, and the DNA can then be replicated each time the host cell divided. But if the new cell is injected directly into the patient’s body, it will be subject to the body’s immune system that will recognize it as foreign and targ... |
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Keywords: recombinant dna technology, lesch nyhan syndrome, target, genetic diseases, gene therapy, sickle cell anaemia, thalassaemia, defective gene, patient therapy, host cell, antenatal diagnosis, cells, gene action, gene defects, gene products, antiviral medication, bob williamson